Browsing by Subject "Neuropeptide Y"

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    Characteristics of distribution of peptide-containing nerve fibres in the atrioventricular valves of the rat
    (Murcia : F. Hernández, 1995) Tsumori, T.; Domoto, T.; Yasui, Y.
    The distribution of vasoactive intestinal polypeptide-, neuropeptide Y-, and calcitonin generelated peptide-irnrnunoreactive nerve fibres was investigated in the atrioventricular valves of the rat. These nerve fibres were visualized by imrnunostaining of whole-mount preparations by the avidin-biotinperoxidase cornplex method. Vasoactive intestinal polypeptide-irnmunoreactive nerve fibres were observed mainly in the anterior cusp of the mitral valve and, to a lesser extent, in the media1 cusp of the tricuspid valve. Numerous neuropeptide Y-immunoreactive nerve fibres were found covering al1 of the cusps. Both types of peptidergic nerve fibre formed dense networks that consisted of interlacing and anastomosing nerve fibres. Calcitonin gene-related peptide-imrnunoreactive nerve fibres were seen in every cusp, but did not fom a fine network. These results provide detailed anatomical information for evaluation of the possible roles of each type of peptide-containing nerve fibre in the function of atrioventricular valves.
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    Nerve fibres containing neuropeptide Y in the atrioventricular valves of Japanese monkey and rat; a light and electron microscopic study
    (Murcia : F. Hernández, 1993) Zhang, W.B.; Domoto, T.; Tsumori, T.; Agawa, S.
    Dense distribution of varicose fibres containing neuropeptide Y-like immunoreactivity (NPYLI) was found in the atrioventricular valves of the Japanese monkey, and moderately in the rat. The immunoelectron microscopy using immunogolds resulted in the localization of NPY-LI within the densecored vesicles which existed with the small clear vesicles in the unmyelinated axons near the endocardium. These NPY-LI-containing fibres may participate in regulation of vasomotor role or other functions of the atrioventricular valves.