Browsing by Subject "Monitoring"
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- PublicationOpen AccessAll that glitters in cfDNA analysis is not gold or its utility is completely established due to graft damage: a critical review in the field of transplantation(MDPI, 2023-06-06) Jiménez Coll, Víctor; El kaaoui El band, Jaouad; Llorente, Santiago; González López, Rosana; Fernández González, Marina; Martínez Banaclocha, Helios; Galián, José Antonio; Botella, Carmen; Moya Quiles, María Rosa; Minguela, Alfredo; Muro, Manuel; Legaz Pérez, Isabel; Ciencias SociosanitariasIn kidney transplantation, a biopsy is currently the gold standard for monitoring the transplanted organ. However, this is far from an ideal screening method given its invasive nature and the discomfort it can cause the patient. Large-scale studies in renal transplantation show that approximately 1% of biopsies generate major complications, with a risk of macroscopic hematuria greater than 3.5%. It would not be until 2011 that a method to detect donor-derived cell-free DNA (dd-cfDNA) employing digital PCR was devised based on analyzing the differences in SNPs between the donor and recipient. In addition, since the initial validation studies were carried out at the specific moments in which rejection was suspected, there is still not a good understanding of how dd-cfDNA levels naturally evolve post-transplant. In addition, various factors, both in the recipient and the donor, can influence dd-cfDNA levels and cause increases in the levels of dd-cfDNA themselves without suspicion of rejection. All that glitters in this technology is not gold; therefore, in this article, we discuss the current state of clinical studies, the benefits, and disadvantages.
- PublicationOpen AccessAnálisis de la carga de entrenamiento previo a una lesión en atletismo de media distancia: Estudio de caso(Universidad de Murcia, Servicio de Publicaciones, 2023) Cardozo, Luis Alberto; Valencia Lara, María; Guerrero Jiménez, Julián; Borja Villamil, Sergio; Reina-Monroy, Javier L.El entrenador deportivo actualmentedispone de una gran variedad de instrumentos y métodos para el control del entrenamiento con el fin de identificar el nivel de carga interna o externa vivenciado por el atleta evitando algún tipo de lesión. El objetivo de este estudio fue explorar la carga de entrenamiento de un atleta de medio fondo previo a una lesión deportiva que generó la suspensión temporal de los entrenamientos. Se utilizó la técnica de entrevista semiestructurada en la fase retrospectiva para indagar sobre los medios y métodos utilizados para el control de la carga. En la fase prospectiva se utilizó el registro de la Frecuencia cardiaca media, la Percepción del esfuerzo de la sesión (sRPE), Índice de monotonía (IM), Índice de fatiga (IF), Niveles de hidratación por el color de la orina y Escala de Somnolencia de Epworth. Los resultados indican que la lesión deportiva ocurrió previo a varias sesiones de alta intensidad expresadas en sRPE y en la semana de mayor volumen, no reflejándose esta situación a través de la FCm, ni en la semana de mayor valor en IM e IF. Adicionalmente, se evidenciaron ciertos niveles de deshidratación e incremento en la escala de somnolencia en las últimas semanas de entrenamiento. Se concluye que algunos medios para el control de la carga de entrenamiento no reflejan la carga real vivenciada por el atleta, por ello, la importancia de implementar varios mecanismos a fin disminuir el riesgo lesivo.
- PublicationOpen AccessEffectiveness of the Sports Training Program Monitor on extracurricular activities of high school students in Central Java(Servicio de Publicaciones. Universidad de Murcia, 2025) Nasuka; Rahayu, Setya; Budiono, Irwan; Ramadhan, Indra; Ulinnuha, Rizam Ahada Nur; Santosa, Teguh; Nadzalan, Ali MD; Pratama, Rivan Saghita; Sin departamento asociadoThe Sports Training Program Monitor is an Android-based application that can record the performance of a workout program performed by students. This study aimed to identify the effectiveness of the application of sports training program monitoring on extracurricular activities of high school students in Jawa Tengah province. This study employed a quantitative research design using the survey method. The sampling technique was purposive sampling, and the research instrument was a questionnaire. The total sample consisted of 128 students (41 male and 87 female). Their mean body weight was 43.76±5.89 kg, height 1.62±0.09 m, and BMI 16.92±3.15 kg/m². The average duration of exercise was 2.03 ± 0.50 weeks. The effectiveness percentage of the application was 95.66% based on 128 samples, indicating that the application has a very high efficiency score. The implementation of sports training program monitoring has a very high level of effectiveness in monitoring student activities in managing extracurricular training. Teachers and students are encouraged to use this application to manage extracurricular sports programs, as it can help develop students’ athletic potential and maintain accurate training records for extracurricular activities.
- PublicationOpen AccessHarmonization of the use of hunting statistics for wild boar density estimation in different study areas: report based on comparison of case studies in different wild boar populations representative of the different management and habitat conditions across Europe.(Wiley, 2019-08-29) ENETWILD-consortium; Vicente, Joaquín; Palencia, Pablo; Plhal, Radim; Blanco Aguiar, José Antonio; Laguna, Eduardo; Soriguer, Ramón; Fernández López, Javier; Podgórski, Tomasz; Petrović, Karolina; Apollonio, Marco; Scandura, Massimo; Ferroglio, Ezio; Zanet, Stefania; Brivio, Fracesca; Keuling, Oliver; Smith, Graham C.; Guibert, Miguel; Villanua, Diego; Rosell, Carme; Colomer, Joana; Armenteros, Jose Ángel; González Quirós, Pablo; Hernández Palacios, Orencio; Ferreres, Javier; Torres, José Antonio; Pareja, Pablo; Martínez-Carrasco Pleite, Carlos; Fafián, José Antonio; Escribano, Fernando; Esteve, Carles; Acevedo Lavandera, Pelayo; Sanidad Animal; Facultades de la UMU::Facultad de VeterinariaHunting statistics can be suitable to determine wild boar density estimates if a calibration with an accepted rigorous method is performed. Here, densities calculated from drive counts during collective drive hunting activities are compared against density values calculated by camera trapping using the random encounter method. For this purpose, we selected 10 study sites in Spain, from North to South representing a diversity of habitats, management and hunting traditions without artificial feeding, plus one study site in Czech Republic where artificial feeding was practiced. Density values estimated from both drive counts and camera trapping were strongly positively correlated (R2=0.84 and 0.87 for linear and non-linear models, respectively) and showed a good agreement. Drive counts data might be therefore used as a density estimate to calibrate models for estimating density in large areas and potentially, to compare densities among areas. For these purposes, there is still the need to harmonise hunting data collection across Europe to make them usable at a large scale. Our results need to be confirmed across a wider number of European populations to provide valid geographical wild boar density predictions across Europe.
- PublicationEmbargoImpact of Contextual Variables On The Representative External Load Profile Of Spanish Professional Soccer Match-Play: A Full Season Study(Wiley, 2020-05-12) Oliva-Lozano, José M.; Rojas-Valverde, Daniel; Gómez-Carmona, Carlos D.; Fortes, Víctor; Pino Ortega, José; Actividad Física y DeporteThe aims of this study were to: (1) identify the representative external load profile of match-play in Spanish professional soccer players by principal components analysis (PCA), and (2) analyse the effect of match location (home vs away), match outcome (win vs draw vs loss) and length of the microcycle (5 vs 6 vs 7 vs 8 vs 9 days) on the external load profile. Data were collected during one season consisting of 42 matches in LaLiga 123 and 11 external load variables were selected after the PCA. TD, total distance covered; DIS0–6: distance from 0 to 6 km/h; DIS21–24: distance from 21 to 24 km/h; HSRD: high-speed running distance above 21 km/h; HSRA: total of high-speed running actions above 21 km/h; VMAX: maximum speed in km/h; Sprints: total of actions above 24 km/h; ACC: total of accelerations; ACCG-avg: average accelerometer G-force; ACCMAX: maximum acceleration (m/s2); DECMAX: maximum deceleration (m/s2). Match location had an impact on HSRD (p < 0.01; ES = 0.05), DIS0–6 (p < 0.01; ES = 0.05), and ACCMAX (p < 0.01; ES = 0.05). Match outcome had a relation to TD (p < 0.01; ES = 0.05), DIS0–6 (p < 0.01; ES = 0.05) and HSRD (p < 0.01; ES = 0.05). Length of the microcycle had an impact on TD (p < 0.01; ES = 0.05), DIS0–6 (p < 0.01; ES = 0.11), ACC (p < 0.01; ES = 0.04) and VMAX (p < 0.01; ES = 0.04). This study provides coaches a selection of variables for match-play analysis, which could represent two-thirds of external load profile. Then, professionals should consider that these contextual variables could have an impact on the external load profile.
- PublicationRestrictedIntracranial pressure monitoring in patients with severe traumatic brain injury: extension of the recommendations and the effect on outcome by propensity score matching(Lippincott, Williams & Wilkins, 2022-09) Castaño-León, Ana M.; Gomez, Pedro A.; Jiménez-Roldán, Luís; Paredes, Igor; Munarriz, Pablo M.; Pérez, Irene Panero; Eiriz Fernández, Carla; Posadas Guillermo García; García Pérez, Daniel; Moreno Gómez, Luis Miguel; Sinovas, Olga Esteban; Posadas García, Guillermo; Lagares, Alfonso; Farmacología; FarmaciaBACKGROUND: Intracranial pressure (ICP) monitoring is recommended for patients with traumatic brain injury (TBI) with a Glasgow Coma Scale (GCS) <9 on admission and revealing space-occupying lesions or swelling on computed tomography. However, previous studies that have evaluated its effect on outcome have shown conflicting results. OBJECTIVE: To study the effect of ICP monitoring on outcome after adjustment of patient’s characteristics imbalance and determine the potential benefit on patients with higher GCS that deteriorates early or in the absence of computed tomography results suggesting high ICP. METHODS: We searched for adult patients with TBI admitted between 1996 and 2020 with a GCS <9 on admission or deterioration from higher scores within 24 hours after TBI. Patients were divided into groups if they fulfilled strict (Brain Trauma Foundation guidelines) or extended criteria (patients who worsened after admission or without space-occupying lesions) for ICP monitoring. Propensity score analyses based on nearest neighbor matching was performed. RESULTS: After matching, we analyzed data from 454 patients and 184 patients who fulfilled strict criteria or extended criteria for ICP monitoring, respectively. A decreased on in-hospital mortality was detected in monitored patients following strict and extended criteria. Those patients with a higher baseline risk of poor outcome showed higher odds of favorable outcome if they were monitored. CONCLUSION: ICP monitoring in patients with severe TBI within 24 hours after injury following strict and extended criteria was associated with a decreased in-hospital mortality. The identification of patients with a higher risk of an unfavorable outcome might be useful to better select cases that would benefit more from ICP monitoring.
- PublicationRestrictedLead and cadmium in wild boar (Sus scrofa) in the Sierra Nevada Natural Space (southern Spain)(Springer, 2016-05-14) Mulero, Rocío; Cano-Manuel, Javier; Ráez-Bravo, Arián; Pérez, Jesús M.; Espinosa, José; Soriguer, Ramón; Fandos, Paulino; Granados, José E.; Romero, Diego; Ciencias SociosanitariasThe aims of the present study were to investigate Pb and Cd levels in tissues of wild boar (Sus scrofa) from the Sierra Nevada Natural Space (SNNS) (southern Spain). Heavy metal concentrations in livers, kidneys and bones from 111 animals were determined by inductively coupled plasma optical emission spectrometry (ICP-OES). Bones and kidneys were the most Pb- and Cd-contaminated tissues, respectively; Cd concentrations were 5.6 times higher in kidneys than in livers. This is the first biomonitoring study of these pollutants in wild boar tissues in the SNNS, and findings indicate that this population is chronically exposed to these heavy metals. The detected Pb and Cd concentrations were lower than those found in many studies performed in Europe on the same species.
- PublicationOpen AccessEl paciente neuroquirúrgico grave. Actuación de enfermería(Murcia : Servicio de Publicaciones de la Universidad de Murcia, 2011) Rodríguez Hernández, IyemaiEl paciente neuroquirúrgico y neurológico son especialmente diferentes de la mayoría de los otros pacientes quirúrgicos. El cerebro tiene un limitado número de respuestas a las lesiones y estas respuestas ocurren en un compartimiento rígido, inflexible. Los cambios ligeros en la presión sanguínea o en la temperatura, que son tolerados con facilidad por la mayoría de los pacientes, pueden causar la destrucción de un variable número de neuronas en el neuroquirúrgico y marcar la diferencia entre una recuperación neurológica completa o un serio déficit neurológico. En la UCI no hay mejor monitor que los ojos vigilantes de la enfermera. Estas observaciones son trascendentes para evaluar el progreso de las complicaciones intracraneales, la asistencia auxiliar continua y experta después del acto quirúrgico es vital para la reducción de la morbilidad de muchas operaciones neuroquirúrgicas. Partiendo de lo anteriormente expuesto nos proponemos resaltar la importancia de la observación continuada por parte del personal de enfermería de este tipo de paciente, contribuyendo así a la detección precoz de las complicaciones que puedan presentarse.
- PublicationOpen AccessPartial contributions and temporal trends of leading causes of death during the last four decades in Spain(Elsevier, 2020-12) Cirera, L; Márquez-Calderón, S; Saez, M; Salmerón, D; Ballesta Ruiz, Mónica; Chirlaque López, María Dolores; Ciencias SociosanitariasObjectives: The study was conducted to assess time trend shifts of leading causes of death and their partial contributions over the years 1975-2016 in Spain. Study design: A longitudinal ecological epidemiologic design was conducted to analyse linear trend period shifts using joinpoint regression as the annual percentage of change (APC) in the period 1975-2016. The partial contributions were illustrated as the rate ratio of a singular-cause to their major-cause shift periods. Results: HIV/AIDS shaped the increasing trend period of infectious diseases in 1989-1995 (APC = 25.3, P < 0.05) and the decreasing trend in 1995-1999 and 1999-2016. Lung cancer fell gradually from 1994 in men (-0.4, P < 0.05); however, in women, the condition continued increasing from 1990 (P < 0.05). Dementia types influenced mental and neurological disease drifts. The recent trend for circulatory periods (1980-2016) was mainly modulated by cardiac ischaemia, with increased partial contributions (25%, 32% and 30%). Traffic accidents defined the descending tendency of external causes. Conclusions: Spain showed a Western pattern in descended rates, including non-decreasing trends in mental and neurological diseases, pancreatic cancer, drug abuse and suicide. Trend shifts and partial contributions illustrated targets for further mortality reduction.
- PublicationRestrictedPartial contributions and temporal trends of leading causes of death during the last four decades in Spain(Elsevier, 2020-12) Cirera, Lluís; Márquez Calderón, S.; Ballesta Ruiz, Mónica; Chirlaque López, María Dolores; Sáez, Marc; Salmerón Martínez, Diego; Mortality working group of the Spanish Epidemiological Association; Ciencias Sociosanitarias; Facultades de la UMU::Facultad de EnfermeríaObjectives The study was conducted to assess time trend shifts of leading causes of death and their partial contributions over the years 1975–2016 in Spain. Study design A longitudinal ecological epidemiologic design was conducted to analyse linear trend period shifts using joinpoint regression as the annual percentage of change (APC) in the period 1975–2016. The partial contributions were illustrated as the rate ratio of a singular-cause to their major-cause shift periods. Results HIV/AIDS shaped the increasing trend period of infectious diseases in 1989–1995 (APC = 25.3, P < 0.05) and the decreasing trend in 1995–1999 and 1999–2016. Lung cancer fell gradually from 1994 in men (−0.4, P < 0.05); however, in women, the condition continued increasing from 1990 (P < 0.05). Dementia types influenced mental and neurological disease drifts. The recent trend for circulatory periods (1980–2016) was mainly modulated by cardiac ischaemia, with increased partial contributions (25%, 32% and 30%). Traffic accidents defined the descending tendency of external causes. Conclusions Spain showed a Western pattern in descended rates, including non-decreasing trends in mental and neurological diseases, pancreatic cancer, drug abuse and suicide. Trend shifts and partial contributions illustrated targets for further mortality reduction.
- PublicationOpen AccessSleep EEG derived from behind-the-ear electrodes (cEEGrid) compared to standard polysomnography: a proof of concept study(Frontiers Media, 2018-11-26) Sterr, Annette; Ebajemito, James K.; Mikkelsen, Kaare B.; Santhi, Nayantara; Monica, Ciro della; Grainger, Lucinda; Atzori, Giuseppe; Revell, Victoria L.; Debener, Stefan; Dijk, Derk-Jan; DeVos, Maarten; Bonmatí Carrión, María de los Ángeles; Anatomía Humana y PsicobiologíaElectroencephalography (EEG) recordings represent a vital component of the assessment of sleep physiology, but the methodology presently used is costly, intrusive to participants, and laborious in application. There is a recognized need to develop more easily applicable yet reliable EEG systems that allow unobtrusive long-term recording of sleep-wake EEG ideally away from the laboratory setting. cEEGrid is a recently developed flex-printed around-the-ear electrode array, which holds great potential for sleep-wake monitoring research. It is comfortable to wear, simple to apply, and minimally intrusive during sleep. Moreover, it can be combined with a smartphone-controlled miniaturized amplifier and is fully portable. Evaluation of cEEGrid as a motion-tolerant device is ongoing, but initial findings clearly indicate that it is very well suited for cognitive research. The present study aimed to explore the suitability of cEEGrid for sleep research, by testing whether cEEGrid data affords the signal quality and characteristics necessary for sleep stage scoring. In an accredited sleep laboratory, sleep data from cEEGrid and a standard PSG system were acquired simultaneously. Twenty participants were recorded for one extended nocturnal sleep opportunity. Fifteen data sets were scored manually. Sleep parameters relating to sleep maintenance and sleep architecture were then extracted and statistically assessed for signal quality and concordance. The findings suggest that the cEEGrid system is a viable and robust recording tool to capture sleep and wake EEG. Further research is needed to fully determine the suitability of cEEGrid for basic and applied research as well as sleep medicine.
- PublicationOpen AccessSpartan: a sparsity-adaptive framework to accelerate deep neural network training on GPUs(Institute of Electrical and Electronics Engineers, 2021-03-22) Dong, Shi; Sun, Yifan; Agostini, Nicolas Bohm; Karimi, Elmira; Lowell, Daniel; Zhou, Jing; Cano, José; Abellán Miguel, José Luis; Kaeli, David; Ingeniería y Tecnología de Computadores; Facultad de InformáticaDeep Neural Networks (DNNs) have emerged as an important class of machine learning algorithms, providing accurate solutions to a broad range of applications. Sparsity in activation maps in DNN training presents an opportunity to reduce computations. However, exploiting activation sparsity presents two major challenges: i) profiling activation sparsity during training comes with significant overhead due to computing the degree of sparsity and the data movement; ii) the dynamic nature of activation maps requires dynamic dense-to-sparse conversion during training, leading to significant overhead. In this article, we present Spartan, a lightweight hardware/software framework to accelerate DNN training on a GPU. Spartan provides a cost-effective and programmer-transparent microarchitectural solution to exploit activation sparsity detected during training. Spartan provides an efficient sparsity monitor, a tile-based sparse GEMM algorithm, and a novel compaction engine designed for GPU workloads. Spartan can reduce sparsity profiling overhead by 52.5× on average. For the most compute-intensive layers, i.e., convolutional layers, we can speedup AlexNet by 3.4×, VGGNet-16 by 2.14×, and ResNet-18 by 2.02×, when training on the ImageNet dataset.
- PublicationRestrictedTemperature of periimplant tissues in clinically successful implants: an observational clinical study in humans(Lippincott, Williams & Wilkins, 2011-08) Sánchez Pérez, Arturo; Moya Villaescusa, María José; Caffesse, Raúl Guillermo; Dermatología, Estomatología, Radiología y Medicina FísicaObjective: The aim of this study was to evaluate periimplant tissue temperature in a successful implant. It has been shown that periimplant disease and mucositis are inflammatory diseases. As such, one of the main clinical signs is the change in temperature. We try to establish normal values of temperature with an easy to use appliance. Design: Fifty-one individuals were enrolled in this study. Only 1 implant per patient was included. The implants were clinically and radiographically examined and diagnosed as clinical successful implants. An infrared ear thermometer was used to measure periimplant temperature (PIT) and the difference with the sublingual temperature (ΔT). These data were analyzed using the Student t test, analysis of variance, and cluster analysis. Results: Statistically significant differences in PIT were observed between the second sextant and the fourth and fifth sextants. These differences were not significant on considering ΔT. In addition, for the clinically and radiographically successful implants, ΔT for all sextants showed a mean of 0.81 (CI, 0.57–1.04). Conclusions: We have found a difference in outcome between periimplant temperature and the temperature differential. PIT depends on the anatomical location, though ΔT is an independent measurement with a value of 0.81°C.
- PublicationOpen AccessTerritorial gaps on quality of causes of death statistics over the last forty years in Spain(BMC, 2024-02-03) Cirera, L; Bañón, RM; Maeso, S; Molina, P; Salmerón, D; Ballesta Ruiz, Mónica; Chirlaque López, María Dolores; Ciencias SociosanitariasBackground The quality of the statistics on causes of death (CoD) does not present consolidated indicators in literature further than the coding group of ill-defined conditions of the International Classification of Diseases. Our objective was to assess the territorial quality of CoD by reliability of the official mortality statistics in Spain over the years 1980–2019. Methods A descriptive epidemiological design of four decades (1980-, 1990-, 2000-, and 2010–2019) by region (18) and sex was implemented. The CoD cases, age-adjusted rates and ratios (to all-cause) were assigned by reliability to unspecific and ill-defined quality categories. The regional mortality rates were contrasted to the Spanish median by decade and sex by the Comparative Mortality Ratio (CMR) in a Bayesian perspective. Statistical significance was considered when the CMR did not contain the value 1 in the 95% credible intervals. Results Unspecific, ill-defined, and all-cause rates by region and sex decreased over 1980–2019, although they scored higher in men than in women. The ratio of ill-defined CoD decreased in both sexes over these decades, but was still prominent in 4 regions. CMR of ill-defined CoD in both sexes exceeded the Spanish median in 3 regions in all decades. In the last decade, women’s CMR significantly exceeded in 5 regions for ill-defined and in 6 regions for unspecific CoD, while men’s CMR exceeded in 4 and 2 of the 18 regions, respectively on quality categories. Conclusions The quality of mortality statistics of causes of death has increased over the 40 years in Spain in both sexes. Quality gaps still remain mostly in Southern regions. Authorities involved might consider to take action and upgrading regional and national death statistics, and developing a systematic medical post-grade training on death certification.