Browsing by Subject "Micro computed tomography"

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    Bone density around titanium dental implants coating tested/coated with chitosan or melatonin: an evaluation via microtomography in jaws of Beagle dogs
    (MDPI, 2021-06-29) López Valverde, Nansi; López Valverde, Antonio; Aragoneses, Juan Manuel; Martínez Martínez, Francisco; González Escudero, María C.; Ramírez, Juan Manuel; Cirugía, Pediatría y Obstetricia y Ginecología
    Peri-implant bone density plays an important role in the osseointegration of dental implants. The aim of the study was to evaluate via micro-CT, in Hounsfield units, the bone density around dental implants coated with chitosan and melatonin and to compare it with the bone density around implants with a conventional etched surface after 12 weeks of immediate post-extraction placement in the jaws of Beagle dogs. Six dogs were used, and 48 implants were randomly placed: three groups—melatonin, chitosan, and control. Seven 10 mm × 10 mm regions of interest were defined in each implant (2 in the crestal zone, 4 in the medial zone, and 1 in the apical zone). A total of 336 sites were studied with the AMIDE tool, using the Norton and Gamble classification to assess bone density. The effect on bone density of surface coating variables (chitosan, melatonin, and control) at the crestal, medial, and apical sites and the implant positions (P2, P3, P4, and M1) was analyzed at bivariate and multivariate levels (linear regression). Adjusted effects on bone density did not indicate statistical significance for surface coatings (p = 0.653) but did for different levels of ROIs (p < 0.001) and for positions of the implants (p = 0.032). Micro-CT, with appropriate software, proved to be a powerful tool for measuring osseointegration.
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    X-ray micro-computed tomography characterization of autologous teeth particle used in postextraction sites for bone regeneration. An experimental study in dogs
    (Wolters Kluwer, 2022-04-26) Calvo Guirado, José Luis; Carlos Villafranca, Félix de; Garcés Villalá, Miguel; García Carrillo, Nuria; Jindal, Vidushi; Martínez Martínez, Francisco; Cirugía, Pediatría y Obstetricia y Ginecología
    Objectives: The objective of this study was to develop a new computed method to characterize and measure the bone density measured in Hounsfield units (HU) of particulate tooth grafts, evaluated by micro-computed tomography (micro-CT) at 2 months of healing. Materials and Methods: Thirty-two dog teeth were crushed with a smart dentin grinder, later implanted in postextraction sites of 4 beagle dogs. Twenty-four cores were taken after 2 months and analyzed by micro-CT (Albira). The methodology used was based on a descriptive statistic of the bone density values measured in HU obtained from the creation of volumes of interest (VOIs) and predefined three-dimensional iso-contours from the images obtained after performing micro-CT of the biopsies of the crushing tooth. Results: The micro-CT allows established the characteristics of the biomaterials by studying the HU. The most predominant type of bone was type D3 density (400–800 HU). There was a light presence of bone-type density D2 and D1 in 2 of the regions studied. Conclusions: Micro-CT could be considered a technique of great value in the characterization of biomaterials based on the HU, after implantation in an in vivo model. The distribution of D1 and D2 particles were located around the bottom and middle part of the alveoli and the D3 and D4 bone particles were in the hole core. Therefore, the method proposed in this study is useful to determine the density of the tooth granulate (dentin grinder) and any other biomaterial.