Browsing by Subject "Medicinal plants"

Now showing 1 - 5 of 5
  • Thumbnail Image
    Publication
    Open Access
    Ethnoveterinary medicine and Ethnopharmacology in the main transhumance areas of Castilla-La Mancha (Spain)
    (Frontiers Media, 2022-05-03) Rivera Núñez, Diego; Verde, Alonso; Fajardo Rodríguez, José; Ríos, Segundo; Alcaraz Ariza, Francisco José; Cárceles Rodríguez, Carlos; Ortiz Sánchez, Juana María; Valdés, Arturo; Ruíz-Gallardo, José Reyes; García-Flores, Aida; Palazón Ferrando, José Antonio; Obón, Concepción; Sanidad Animal
    In this study, we document the practices of ethnoveterinary medicine and ethnopharmacology in the context of traditional transhumance routes that cross Castilla La Mancha from north to south. Transhumance is a type of grazing system that allows advantage to be taken of winter pastures (wintering places) and summer pastures by seasonal movement, twice a year, of cattle and their shepherds. Our study is based on over 200 interviews (from 1994 to 2021) conducted in 86 localities along eight major transhumance routes “cañadas reales” and 25 other minor transhumance routes, and involved 210 informants, 89 single and 121 groups, and 562 individuals, of which the majority were men. Sixty-three recorded pathologies and their treatments are discussed. Two hundred and two species and substances, belonging to 92 different families, have been recorded from the interviews, of which most are plants. Amid the toxic plant species, the most cited in the interviews are Erophaca baetica (L.) Boiss., Lupinus angustifolius L., and Oenanthe crocata L. Some of the species reported as toxic were reservoirs of pathogens or markers for dangerous areas. One of the fields most widely covered in our study is that of prevention, protection, and control of endo- and ectoparasites. This control is carried out mainly by means of aromatic plants. As a polyvalent species, Daphne gnidium L. is outstanding, and it contributes one-tenth of the records of our study. Among the species of fundamentally therapeutic use, Cistus ladanifer L. stands out by far. Principal Coordinate Analysis (PCoA) based on the repertories of ingredients, separates the routes whose most important sections run through siliceous terrain with its characteristic flora, especially in the provinces of Ciudad Real and Toledo, from the routes that run through the limestone terrain of Albacete and Cuenca, and link the Eastern Mancha and the “Serranía de Cuenca” with Andalusia and the Spanish Levant.
  • Thumbnail Image
    Publication
    Open Access
    Neurofuzzy logic predicts a fine-tuning metabolic reprogramming on elicited Bryophyllum PCSCs guided by salicylic acid
    (Frontiers Media, 2022-09-23) Lozano-Milo, Eva; Zhang, Leilei; Landin, Mariana; Lucini, Luigi; Gallego, Pedro P.; Miras Moreno, Begoña; García Pérez, Pascual
    Novel approaches to the characterization of medicinal plants as biofactories have lately increased in the field of biotechnology. In this work, a multifaceted approach based on plant tissue culture, metabolomics, and machine learning was applied to decipher and further characterize the biosynthesis of phenolic compounds by eliciting cell suspension cultures from medicinal plants belonging to the Bryophyllum subgenus. The application of untargeted metabolomics provided a total of 460 phenolic compounds. The biosynthesis of 164 of them was significantly modulated by elicitation. The application of neurofuzzy logic as a machine learning tool allowed for deciphering the critical factors involved in the response to elicitation, predicting their influence and interactions on plant cell growth and the biosynthesis of several polyphenols subfamilies. The results indicate that salicylic acid plays a definitive genotype-dependent role in the elicitation of Bryophyllum cell cultures, while methyl jasmonate was revealed as a secondary factor. The knowledge provided by this approach opens a wide perspective on the research of medicinal plants and facilitates their biotechnological exploitation as biofactories in the food, cosmetic and pharmaceutical fields.
  • Thumbnail Image
    Publication
    Open Access
    Plantas medicinales utilizadas en la salud infantil
    (Servicio de Publicaciones de la Universidad de Murcia, 2011) Souza, ADZ.; Ceolin, T.; Vargas, NRC.; Heck, RM.; Vasconcellos, CL.; Borges, AM.; Mendieta, MC.
    Identificar las plantas medicinales utilizadas en la salud infantil por familias de agricultores de base ecológica de la región Sur de Río Grande do Sul, Brasil. El enfoque de investigación es cualitativo, exploratorio y descriptivo, con datos recogidos de enero a mayo de 2009. Los sujetos fueron ocho familias de agricultores, residentes en los municipios de Pelotas, Morro Redondo, Canguçu y Arroio do Padre. Seis plantas fueron citadas (Chrysanthemun cinerariifolium, Foeniculum vulgare, Acca sellowiana, Citrus sp. Origanun sp. Sambucus spp.), y sólo de una (Foeniculum vulgare) encontramos estudios farmacológicos comprobando lo que los sujetos de la investigación referían. Es muy importante que el profesional enfermero tenga conocimientos sobre plantas medicinales para transmitir la información pertinente sobre la forma de preparación, dosis e indicaciones relativas a las plantas utilizadas en la salud infantil.
  • Thumbnail Image
    Publication
    Restricted
    The metabolomics reveals intraspecies variability of bioactive compounds in elicited suspension cell cultures of three Bryophyllum species
    (Elsevier, 2021-02-15) García-Pérez, Pascual; Lucini, Luigi; Gallego, Pedro P.; Miras Moreno, Begoña; García Pérez, Pascual
    In this work, the combination of elicited plant suspension cultured cells (PSCCs) with untargeted metabolomics establishes a powerful, cutting-edge strategy to unravel the effects of elicitors on the biosynthetic potential of medicinal plants, as Bryophyllum sp. The PSCC technology constitutes a successful biotechnological system for the study and production of bioactive compounds throughout the inclusion of elicitors with the ability to modulate secondary metabolism. The use of methyl jasmonate (MJ) and salicylic acid (SA) as abiotic elicitors on bryophyllum PSCCs, resulted in differential effects on cell growth and secondary metabolism, depending on the species, including synergistic and antagonistic effects. This fact suggests that both elicitors play a pleiotropic effect on plant secondary metabolism, showing complex interactions, according to the UHPLC-QTOF mass spectrometry profiling. Thus, the combination of both elicitors induced a strong synergistic on B. daigremontianum PSCCs, with 2272 putatively annotated compounds, whereas it caused a negative effect on the secondary metabolism of B. × houghtonii PSCCs, being MJ the only elicitor driving a positive effect, presenting 2972 annotated compounds. Meanwhile, B. tubiflorum PSCCs did not show a significant modulation of secondary metabolism, with 1521 annotated compounds. The metabolite annotation indicated that three families of secondary metabolites were mainly affected by elicitation: phenolic compounds constituted the most affected family by elicitation, mainly represented by flavonoids and lignans; N-containing compounds included glucosinolates, amines, and alkaloids, reported to Bryophyllum sp. for the first time; and terpenoids included mainly phytoalexins and saponins. The results depict a deep genotype-dependent metabolomic reprogramming of secondary metabolism in response to elicitors, thanks to the application of untargeted metabolomics. This knowledge will allow the consideration of Bryophyllum sp. as a valuable source of bioactive compounds, with the potential associated to PSCCs, for being included in food, cosmetic, and pharmaceutical applications.
  • Thumbnail Image
    Publication
    Open Access
    Uso de plantas medicinales en el cuidado de la salud: la producción científica de tesis y disertaciones de enfermería brasileña
    (Murcia: Servicio de Publicaciones de la Universidad de Murcia, 2015) Heisler, Elisa Vanessa; Budó, Maria de Lourdes Denardin; Schimith, María Denise; Badke, Marcio Rossato; Ceolin, Silvana; Heck, RM.
    Este estudio tuvo como objetivo identificar la tendencia de la producción científica de la enfermería brasileña en tesis y disertaciones, en relación con el uso de plantas medicinales para el cuidado de la salud.Se trata de un estudio cualitativo, de carácter descriptivo, estructurado a través de una revisión narrativa de la literatura. Los resultados se obtuvieron mediante la búsqueda en línea, que se produjo en mayo de 2013, en el Portal de tesis y disertaciones de la Coordinación de Perfeccionamiento de Personal de Nivel Superior (CAPES). Se seleccionaron conforme criterios de inclusión y exclusión 19 producciones. Tras el análisis las producciones fueron separadas por tendencias: Conocimientos y prácticas populares acerca del uso de las plantas medicinales, el conocimiento profesional y prácticas en cuanto al uso de las plantas medicinales e Investigación de la eficacia de las especies. En general, los resultados demuestran la importancia de la participación de los profesionales de la salud, especialmente los enfermeros, en estudios e investigaciones que involucran el uso de plantas medicinales, actuando como facilitador en el rescate de los conocimientos tradicionales y su validación científica.