Browsing by Subject "Ivermectin"

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    Congenital bilateral clinical anophthalmia and brachygnathia superior in a fighting bull calf
    (Wiley, 2023-05-18) Sanes, José Manuel; Bueno, Juan Manuel; Jódar, Carlos de; Soler, Marta; Bayón, Alejandro; Párraga Ros, Ester; Seva Alcaraz, Juan; Anatomía y Anatomía Patológica Comparadas
    This study describes a case of a 20-day-old male fighting bull with bilateral clinical anophthalmia and brachygnathia superior whose dam was 12.5 years old and was mistakenly dewormed with ivermectin intramuscularly in the first third of gestation in a livestock farm. A macroscopic examination of the carcass was performed, with a special focus on the ocular components. Eyeball remains were found in both orbits and a histopathological examination was performed on them. Antibodies by serological study against bovine herpes virus-1, respiratory syncytial virus and bovine viral diarrhea virus for both the cow and the calf were not detected. The calf had small orbits and inside them a white and brown mass of soft consistency. Microscopically, abundant muscular and adipose tissue was observed, alongside nervous structures and vestiges of ocular structures with stratified epithelium and abundant connective tissue with glands. No evidence that this congenital bilateral anophthalmia had infectious or hereditary origin was found. By contrast, the malformation could be related to the treatment with ivermectin during the first month of gestation.
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    Effect of mebendazole and ivermectin on the shedding of nematode eggs by three species of gazelles (Gazella dama mhorr, G. cuvieri, and G. dorcas)
    ( American Association of Zoo Veterinarians, 1995-07-07) Abaigar, Teresa; Ortiz, Juana; Cano, Mar; Martínez-Carrasco Pleite, Carlos; Albaladejo, Antonio; Alonso de Vega, Francisco-Domingo; Sanidad Animal; Facultades de la UMU::Facultad de Veterinaria
    Mebendazole and ivermectin were studied for the control of gastrointestinal helminthiasis in three species of captive gazelles: Gazella dama mhorr, G. cuvieri, and G. dorcas. Ivermectin was given s.c. in a single 0.2-mg/kg live-weight dose and mebendazole was given in three dosages based on species: G. dorcas, 14 mg/kg; G. cuvieri, 6 mg/kg; and G. dama, 3 mg/kg orally twice daily for 3 consecutive days. Each drug was tested in 13 individuals of each species; 13 additional individuals served as untreated controls. Helminths detected by fecal examination and culture were species of Trichuris, Ostertagia, Cooperia, Trichostrongylus, Nematodirus, and Strongyloides. The prevalence among the total gazelle population was: Trichuris, 55%; Nematodirus, 26%; and other nematodes, 84%. After treatment with mebendazole, the nematode egg counts and the number of animals shedding eggs decreased moderately. After ivermectin treatments, there were marked decreases in the amount of eggs being shed and the number of animals shedding eggs of these nematodes.
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    Experimental ivermectin treatment of sarcoptic mange and establishment of a mange-free population of spanish ibex
    (Wildlife Disease Association, 2001-10) León Vizcaíno, Luis; Cubero, M. José; González Capitel, Emilio; Simón, Miguel Ángel; Pérez, Linarejos; Ruiz de Ybáñez Carnero, María del Rocío; Ortiz Sánchez, Juana; González Candela, Mónica; Alonso de Vega, Francisco; Sanidad Animal
    Ivermectin was used to treat sarcoptic mange in Spanish ibex (Capra pyrenaica hispanica). Its therapeutic effectiveness was analyzed when it was administered through subcutaneous injection, to sick animals in the consolidation stage of mange (third phase) and, with double injections to chronically affected animals (fourth phase) at a dosage of 0.2 or 0.4 mg/kg body weight (bw). Three wk after treatment, the animals in the third phase of mange treated with a high dose (0.4 mg/kg bw) of ivermectin were completely cured. The same result was achieved after 4 wk of treatment in those animals in phase 3 of mange when 0.2 mg/kg body weight was used. Double injection with ivermectin, even at high doses, did not guarantee the complete cure of all cases of sarcoptic mange in the chronic stage (phase 4); only three of six animals were free of Sarcoptes scabiei. The second experiment consisted on the application of a sanitation program in order to obtain a population of Spanish ibex free from S. scabiei, starting with free-ranging animals, some of them healthy and others sick. After capture the animals were classified as chronically ill, in which case they were excluded from the program, mite carriers and healthy specimens. All the animals were treated first topically with foxim (500 mg/l) and subcutaneously with ivermectin (0.4 mg/kg bw). The infected animals were housed in the treatment pen, and received two doses of ivermectin (0.2 mg/kg bw) at an interval of 15 days, then spent 15 days in the quarantine pen, where they received a further dose before they were included in the pool of healthy animals, and immediately were placed in the quarantine phase. The sanitation we implemented was fully effective in curing the affliction of Spanish ibex affected by S. scabiei