Browsing by Subject "Intraneural"

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    Mature congenital intraneural teratoma in cerebellum of pig
    (Universidad de Murcia. Departamento de Biología Celular e Histología, 2019) Soto Domíngue, Adolfo; Rodríguez Rocha, Humberto; García García, Aracely; Saucedo Cárdenas, Odila; Rodríguez Tovar, Luis E.; Castillo Velázquez, Uziel
    The biological behavior of teratomas depends on several interdependent clinical and epidemiological variables such as age at diagnosis, sex, tumor microenvironment, and tumor morphology, among others. All these variables are correlated to different cytogenetic and molecular aberrations (Harms et al., 2006). There are null reports of teratomas in pigs. The aim of this study was to characterize the tissues present in a mature congenital intraneural teratoma in the cerebellum area of a Landrace female pig of 6-7 weeks old. In this study, tissue control samples were used to validate each staining method. Sections from the teratoma showed normal histology of the cerebellum, including rounded Purkinje neurons with abundant cytoplasm, euchromatic nuclei, and prominent nucleoli; glial cells with a scarce amount of cytoplasm and small and highly basophile-nuclei (compact chromatin) and axonal tracts (white matter). Interestingly, we also observed areas with tissues different from the nervous tissue, including bundles of well-defined skeletal muscle fibers with a striated pattern and peripheral nuclei; hyaline cartilage plaques, with prominent presence of chondrocytes in their lagoons forming isogenous groups surrounded by a territorial and interterritorial matrix; trabeculated bone tissue; and adipocytes, which are ringshaped cells with peripheral flattened nuclei, as a result of the presence of a central large lipid droplet. To our knowledge, this study is the first to describe a congenital intraneural mature teratoma in the cerebellum of a pig.