Browsing by Subject "Interferon"

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    Interferón: mecanismos bioquímicos de formación y acción
    (Universidad de Murcia, Servicio de Publicaciones, 1985) Galindo Cascales, Jesús David; Solano Muñoz, Francisco; Iborra Pastor, José Luis; Facultad de Biología
    The group of proteins known as interferons is now one of the most important fields of research in Biology. This review summarizes our present knowledge about the biochemical mechanisms of synthesis and action of interferons. Discovered by Isaacs and Lindenmann as agents of vira1 interference, today it is known that they are produced by most of vertebrates in response to a lot of appropiate stimuli. Here we discuss the ckssification of interferons, the human genes in which the information for their production and for the protein machinery involved in their response is contained, the biochemical mechanisms of the interferon production in ceUs treated by an inductor, and those developed in the surrounding cells when interferon is secreted. We conclude with the expression of therapeutic use of interferon and the existente of similar proteins in vegetal species.