Browsing by Subject "Eye"
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- PublicationOpen AccessA Comparison Between Refraction From an Adaptive Optics Visual Simulator and Clinical Refractions(2020) Tabernero de Paz, Juan Francisco; Otero, C.; Pardhan, S.; Electromagnetismo y Electrónica
- PublicationOpen AccessAplicaciones del suero autólogo en la consulta del servicio de oftalmología en el Hospital Donostia.(Murcia : Servicio de Publicaciones de la Universidad de Murcia, 2008) Solórzano Sánchez, M.; Pernas Pena, A.; Zabala Largo, AI.Introducción: La etiología del ojo seco se relaciona con la falta de factores de crecimiento, responsables de mantener una adecuada proliferación de la superficie del epitelio ocular. En la sangre se encuentran estos componentes, por lo que la utilización del suero autólogo es una opción terapéutica para el ojo seco. El suero autólogo es un preparado a base de tu propia sangre centrifugada a 3.000 rev/minuto. Objetivo: Protocolizar el procedimiento de prescripción, elaboración, y dispensación de colirio de suero antólogo. Material y Métodos: En el año 2004 se acordó con el Servicio de Oftalmología definir la protocolización del colirio de suero autólogo. Resultados: Entre mayo de 2004 y abril de 2006 se ha tratado a 42 pacientes. En el 2004 se elaboraron colirios para 11 pacientes, en el 2005 para 32, y hasta abril del 2006 para 22. El 50% de los pacientes ha necesitado ser retratado al menos una vez, siendo los casos con EICH, con una media de 8 dispensaciones por paciente, los más retratados. Conclusiones: El aumento de la demanda justifica la protocolización de este preparado. La elaboración y dispensación del colirio por parte del Servicio de Farmacia garantiza la esterilidad y estabilidad del mismo, y posibilita la atención farmacéutica orientada a la mejora de la eficacia y correcto uso del colirio. Todos los pacientes tratados con Suero Autólogo han mejorado de su patología de ojo seco. Han mejorado en su calidad de vida (menos molestias en la visión, mejor visión).
- PublicationOpen AccessConstrucción narrativa de Don Juan en "El alma y el cuerpo de Don Juan" de Alberto Insúa.(Universidad de Murcia, EDITUM, 2021) Fidalgo Giraldez, AndreaEn este trabajo se analiza la figura del seductor que Alberto Insúa remitifica en su obra El alma y el cuerpo de don Juan a través de un análisis narratológico centrado en la descripción del personaje desde las distintas perspectivas que aparecen en el texto. Se analiza cómo el narrador, el propio don Juan y los demás personajes definen y construyen las características corporales y espirituales del héroe, mostrando la decadencia física y moral en la que se encuentra. Se profundiza, además, en la simbología que el “ojo” presenta en esta obra, entendiendo que, junto con la mirada narrativa, contribuye a mostrar a un burlador derrotado que ya no encaja en la sociedad en la que se incluye y que por tanto, siguiendo la tradición mítica, debe morir y ser condenado, pero que, aún así, continúa vigente gracias a sus reescrituras míticas.
- PublicationOpen AccessEtiology of the developing eye in myelencephalic blebs (my) mice(Murcia : F. Hernández, 1992) Center, Elizabeth M.; Polizotto, René S.The etiology of the eye defects in myelencephalic blebs (my) mutant mice has been poorly understood for almost seventy years. Embryos from 9 to 14 M days of gestation were subjected to Alcian blue 8GX staining for acidic glycosaminoglycan deposition in basement membrane structures of the developing eye in my stock and control specimens. In addition 12 day embryos were subjected to avidinbiotin- peroxidase labelling for laminin. At 9 - 9 M days of gestation more Alcian blue positive extracellular matrix was found in the region between the optic vesicle and the overlying putative lens ectoderm in the my stock embryos. By 12 days, there was an irregular and lesser amount of deposition of glycosaminoglycans in the len's capsule and in the «inner lirniting membrane~ of the presumptive neural retina; however, the deposition of laminin appeared to be greater in the inner lirniting membrane of the my eye. By 14 days, the damage to the eye in the my embryos can be quite extensive, and the deposition of glycosaminoglycans was very meager in this situation. It appears that irregular deposition of glycosaminoglycans in the extracellular matrix and possible increase in the amount of laminin in basement structures in my embryos indicate disruption of the normal histochemistry involved in the development of the eye. Altered histochemistry may in turn indicate changes in permeability between cells of the developing tissues which result in the blebbing.
- PublicationOpen AccessFine structure of the pecten oculi of the barred owl (Strix varia)(F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología, 1996) Smith, B. J.; Smith, S. A.; Braekevelt, C. R.The pecten oculi of the barred owl (Strix varia) has been examined by light and transmission electron microscopy. The pecten in this species is of the pleated type and is small in comparison to the size of the ocular globe. The pecten consists of 8-10 accordion-like folds that are linked apically by a pigmented tissue bridge. Each fold contains numerous capillaries, larger supply and drainage vessels, and abundant pleomorphic melanocytes. Most of these capillaries are extremely specialized vessels that possess plentiful microfolds on both the luminal and abluminal surfaces. Some capillaries however display only a few microfolds. The endothelial cell bodies are extremely attenuated, with most organelles located near the nucleus. All capillaries are surrounded by a very thick fibrillar basal lamina, which is thought to provide structural support to these small vessels. Pericytes are commonly found within these thickened basal laminae. Numerous melanocytes are also present, with processes that form an incomplete sheath around the capillaries. These processes are also presumed to provide structural support for the capillaries. As in other avian species, the morphology of the barred owl pecten is indicative of extensive involvement in substance transport. When compared to the pecten of more visually-oriented species, this pecten is smaller, has fewer folds, and displays a reduced number of microfolds within the capillaries. In these and other features, the barred owl pecten is similar to the pecten of the great horned owl (Bubo virginianus).
- PublicationOpen AccessHistopathological changes in the eyes in systemic lupus erythematosus: An electron microscope and immunohistochemical study(Murcia : F. Hernández, 2005) Nag, T.C.; Wadhwa, S.This paper reports the histopathological findings in the eyes of a 26-year-old female patient diagnosed with systemic lupus erythematosus (SLE) with peripheral neuropathy. The patient had no significant ocular problems. She died of pneumonia after two years of suffering. The eyeballs were procured at autopsy and the retina, choroid and optic nerve processed for light and electron microscopy, and immunohistochemistry for immunoglobulin G (IgG), glial fibrillary acidic protein (GFAP), calbindin and parvalbumin. Histologically, there was haemorrhaging in the retinal nerve fibre layer. Ultrastructurally, the axons of this layer were swollen, and contained an unusual accumulation of microtubules and smooth endoplasmic reticulum. There were degenerative changes in the pericytes and smooth muscle cells of blood vessels. The capillary lumen was partially obliterated, and contained IgG, which was also detected throughout the choroid and wall of choroidal arterioles. The latter and Bruch’s membrane showed fibrin deposits. The optic nerve showed infiltrated mononuclear cells near the degenerated axons, these axons lacked immunoreactivity to calbindin and parvalbumin. Compared to the control, the connective tissue sheaths of the central retinal vessels possessed a vast number of proliferated fibroblast cells, and trichrome staining showed transmural vessel scarring. Dense GFAP immunoreactivity was observed surrounding the vessel wall. These pathological changes are due to impaired blood circulation caused by haemorrhaging and vasculitis, and vessel occlusion by fibrin. The nature of the changes observed tends to indicate that a regular, thorough ophthalmic examination should be conducted even in the absence of significant ocular symptoms in SLE.