Browsing by Subject "Endocrine system"

Now showing 1 - 2 of 2
  • Thumbnail Image
    Publication
    Open Access
    ACE2 in male genitourinary and endocrine systems: Does COVID-19 really affect these systems?
    (Universidad de Murcia, Departamento de Biologia Celular e Histiologia, 2023) Xu, Chen Shuo; Yang, Wan Xi
    The virus that causes COVID-19 (Corona Virus Disease 2019), SARS-CoV-2 (Severe Acute Respiratory Syndrome Coronavirus 2), is causing a worldwide pandemic, posing a substantial threat to human health. Patients show signs of pneumonia, ARDS, shock, acute cardiac injury, acute kidney injury and other complications. The SARS-CoV-2 receptor is angiotensin converting enzyme 2 (ACE2), which is an important component of the renin-angiotensin system (RAS). In addition, TMPRSS2 or other cofactors are needed to allow the virus to enter the host. Clinical patients have exhibited varying degrees of genitourinary and endocrine system damage, and some studies have also reported potential risks to the genitourinary and endocrine systems. This article reviews the mechanism underlying SARS-CoV-2 infection and the current studies on the male genitourinary and endocrine systems and proposes that more attention should be directed towards human reproductive and endocrine health during the SARS-CoV-2 epidemic.
  • Thumbnail Image
    Publication
    Open Access
    Effects of temperature regime (daily thermocycles versus constant) on growth and the ontogeny of the daily rhythms of expression of digestive factors of Nile tilapia (Oreochromis niloticus)
    (Elsevier, 2020-11-15) Espirito Santo, Amanda Hastenreiter; Alba, Gonzalo de; Reis, Yane; Costa, Leandro; Sánchez Vázquez, Francisco Javier; Luz, Ronald Kennedy; Paula, Ribeiro; López Olmeda, José Fernando; Fisiología
    Environmental factors present cyclic variations during the day. Of them, high temperatures occur in the light phase, whereas low temperatures take place at night, which is known as thermocycle. Although applying thermocycles to fish larvae improves growth in some species, nothing is known about the impact during the early development of the digestive system. The aim of the present research was to investigate the effect of different temperature regimes, cycling versus constant, on the daily rhythms of digestive factors and growth of Nile tilapia (Oreochromis niloticus) larvae. For this purpose, fertilized eggs were divided into two groups: one under a thermocycle (TC) of 31ºC:25ºC day:night and other group at constant temperature of 28ºC (CTE). Photoperiod was set at 12:12h light/dark cycle. Larvae length was measured on 4, 8 and 13 days post-fertilization (dpf). Larvae samples were collected every 4 h during a 24-hour cycle on 4, 8 and 13 dpf. The expression levels of pepsinogen, chymotrypsinogen, trypsinogen, lipase, maltase, isomaltase, npy and cck were analyzed by qPCR. The results showed that larval growth was greater when larvae were reared at TC than at CTE. Moreover on 13 dpf, most analyzed genes (chymotrypsinogen, lipase, maltase, isomaltase, npy and cck) displayed daily rhythms in the TC group, but not in CTE, with most acrophases located around mealtime. These rhythms could explain the higher growth rate observed in the TC larvae due to improved feed digestion and utilization. The results can be useful for improving the rearing protocols used in larviculture and to enhance production performance.