Browsing by Subject "Coronary disease"

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    “Ahí me aguanté mi dolor”. Contexto sociocultural y económico de mujeres con síndrome con coronario residentes en Cali y otros municipios del Valle del Cauca
    (2015) Valencia Micolta, Susana Genith; Rodríguez Torres, Estela
    La investigación forma parte del “Estudio Multicéntrico, Comparación de la caracterización de los síntomas de angina en la mujer en ocho ciudades de Colombia”. Aborda las condiciones de desigualdad en empleo, educación, género y etnia, situaciones de violencia y desplazamiento forzoso, factores fisiológicos que desencadenan una serie de síntomas y aparición del síndrome coronario, angina e infarto agudo de miocardio. Objetivo: Determinar aspectos socioculturales y económicos que influyen en la aparición de síntomas de angina en mujeres de Cali y municipios del Valle del Cauca Material y método. Estudio descriptivo con abordaje cualitativo, en 23 mujeres. Con criterios de haber experimentado molestia, dolor o sensación de disconfort torácico, hemodinámicamente estables, arteriografía coronaria con lesión de vasos mayor de 70%, y postsíndrome coronario agudo. Las entrevistas son analizadas con técnica de análisis de contenido de Klipendorf y Teoría de Síntomas Desagradables de Lenz y colaboradores Resultados. Los síntomas desagradables, tienen relación con antecedentes fisiológicos y factores influyentes del ambiente físico, familiar y social. Emergen categorías acerca de responsabilidades laborales y domésticas, asumir roles, apoyo a la familia y conviviendo con sus dificultades, viviendo con incertidumbre e inseguridad, relaciones con el entorno, cumpliendo con el tratamiento. Conclusión. El modo de vida en las mujeres que padecen de síndrome coronario agudo es un factor influyente en el agravamiento de los síntomas. Las mujeres están expuestas a experiencias y entornos desventajosos en condiciones de vulnerabilidad e inequidad.
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    Clinical relevance of sST2 in cardiac diseases
    (2015-05-09) Pascual Figal, Domingo A.; Lax, Antonio; Perez Martinez, Maria T.; Asensio Lopez, Maria del Carmen; Sanchez Mas, Jesus; Lax Pérez, Antonio Manuel; Medicina
    ST2 has two main isoforms, ST2L and soluble isoform of ST2 (sST2), by alternative splicing. The interaction between interleukin (IL)-33 and the transmembrane isoform ST2L is up-regulated in response to myocardial stress and exerts cardio-protective actions in the myocardium by reducing fibrosis, hypertrophy and enhancing survival. The circulating isoform sST2, by sequestering IL-33, abrogates these favorable actions and will be elevated as a maladaptive response to cardiac diseases. Indeed, circulating sST2 concentrations correlate with a worse phenotype of disease including adverse remodeling and fibrosis, cardiac dysfunction, impaired hemodynamics and higher risk of progression. In patients with acute and chronic heart failure, sST2 concentrations are strongly predictive of death, regardless of the cause and left ventricle (LV) ejection fraction, and contribute relevant information in addition to other prognosticators and biomarkers, as natriuretic peptides or troponins. sST2 also retains prognostic information in the setting of acute myocardial infarction (AMI) and predicts cardiovascular death and risk of heart failure (HF) development in these patients. sST2 could also be a promising tool to stratify the risk of sudden cardiac death (SCD) in patients with depressed LV ejection fraction. Therefore, sST2 represents a clinically relevant biomarker reflecting pathophysiological processes and contributing predictive information in the setting of several cardiovascular diseases, and especially in patients with HF.
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    Midterm clinical and echocardiographic results with patch glue repair of left ventricular free wall rupture
    (Lippincott, Williams & Wilkins, 2003-09-09) Cánovas López, Sergio; Lim, Eric; Dalmau, María J.; Bueno, María; Buendía, Jose; Hornero, Fernando; Gil, Oscar; García, Rafael; Paya, Rafael; Pérez, Jose; Echanove, Ildefonso; Montero, Jose; Cirugía, Pediatría y Obstetricia y Ginecología
    Background— Left ventricular free wall rupture (LVFWR) is a dramatic complication after myocardial infarction. We present our mid-term clinical and echocardiographic results of LVFWR with an epicardial patch without cardiopulmonary bypass. Methods— From February 1993 to May 2001, 17 patients underwent surgery for LVFWR. The mean age±SD of 12 males and 5 females was 68±10 years. All patients presented for emergency surgery with cardiac tamponade confirmed on echocardiography. After opening the chest and identification of the site of rupture, a Goretex patch was fashioned and applied with enbucrilate surgical glue. Results— Effective control of bleeding was achieved in all cases. There were no on-table deaths. The operative (30 day) mortality was 23.5% (4/17). One death occurred because of patch failure, two because of cardiogenic shock, and one from pneumonia. On follow-up at a median of 2.2 years (interquartile range, 1.1 to 4.3 years), two further deaths occurred, one from myocardial infarction and another of undetermined etiology. Echocardiography did not reveal any evidence of restriction to left ventricular free wall motion. Conclusions— Patch glue repair is expedient, simple and effective; with no adverse effects on mid-term ventricular dynamics. In view of superior published results to infarctectomy and repair with extra corporeal circulation, it should be considered to be the initial procedure of choice for the surgical repair of LVFWR.