Browsing by Subject "Autoacetylation"

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    The protein acetyltransferase PatZ from Escherichia coli is regulated by autoacetylation-induced oligomerization
    (2015) Castaño Cerezo, Sara; Bernal Sanchez, Vicente; Manjón Rubio, Antonio; Fernández Espín, Vanesa; García de la Torre, José; Cánovas Díaz, Manuel; Diego Puente, Teresa de; Gallego Jara, Julia; Bioquímica y Biología Molecular B e Inmunología
    Background: PatZ is the main Escherichia coli acetyltransferase and control acetyl-CoA synthetase (Acs) activity. Results: The kinetic and structural PatZ oligomer characteristics were determined. Conclusion: PatZ is a stable tetramer and forms an active octamer by autoacetylation to increase its stability. Significance: PTMs by acetylation have structural and functional roles in the cell.