Browsing by Subject "Acetals"

Now showing 1 - 1 of 1
  • Thumbnail Image
    Publication
    Open Access
    Pd(II)-catalyzed deprotection of acetals and ketals containing acid sensitive functional groups
    (Elsevier, 2014-02-05) Juliá Hernández, Francisco; Arcas, Aurelia; Vicente, José; Química Inorgánica
    The pincer complex [Pd(C1,O1,N1-L)(NCMe)]ClO4 (L = monoanionic ligand resulting from deprotonation of the acetyl group of the dimethyl monoketal of 2,6-diacetylpyridine) is used for the high-yield and selective catalytic hydrolysis of aliphatic, aromatic, cyclic and acyclic dimethyl-acetals, - ketals and dioxolanes, even in the presence of large substituents. Other protecting groups, as THP or TBDMS, or very acid-sensitive alcohols were not affected. The catalyst is easily prepared in high yield from Pd(AcO)2 and 2,6-diacetylpyridinium perchlorate stable to air and moisture, easily and fully recoverable and reusable.