Histology and histopathology Vol.33,nº11 (2018)
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Browsing Histology and histopathology Vol.33,nº11 (2018) by Subject "Human papillomavirus"
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- PublicationOpen AccessThe relationship between esophageal cancer, chagasic megaesophagus and HPV: myths, tales or reality?(Universidad de Murcia. Departamento de Biología Celular e Histología, 2018) Munari, Fernanda Franco; Cruvinel Carloni, Adriana; Sammartino Mariano, Vânia; Syrjanen, Kari; Reis, Rui Manuel; Longatto Filho, AdhemarA supposed role for persistent high-risk human papillomavirus (HPV) infection in esophageal squamous cell carcinoma (ESCC) etiology has been suggested by a number of studies. Concomitantly, megaesophagus induced by the Trypanosoma cruzi cellcycle activity also shows a potential association with ESCC. This review discusses esophageal cancer and the potential association between chagasic megaesophagus and HPV as risk factors for ESCC development.