(2023-06-28) Valdor Alonso, Rut; García Bernal, David; Moraleda Jiménez, José María; Martínez Pérez, Salvador; Bioquímica y Biología Molecular B e Inmunología
The present invention refers to a substantially pure population of pericytes, or cell suspension comprising pericytes, wherein the pericytes are at least 80% of the total cell population or suspension, characterized in that CMA is inhibited, for example by inhibiting the expression or deleting the gene LAMP2A. In a preferred embodiment, said population or suspension of pericytes is used as a medicament, for instance in the treatment of cancer, preferably glioblastoma