Histology and histopathology, Vol.41, Nº2, (2026)

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Open Access
Recent progress in macrophage- mediated tendon injury and healing
(Universidad de Murcia, Departamento de Biologia Celular e Histiologia, 2026) Yining Zhang; Yanzhao Dong; Xiaodi Zou; Ahmad Alhaskawi; Fangyu Yi; Sohaib Hasan Abdullah Ezzi; Vishnu Goutham Kota; Mohamed Hasan Abdulla Hasan Abdulla; Haiying Zhou; Alenikova Olga; Sahar Ahmed Abdalbary; Jinhui Liang; Hui Lu; Weijie Zhou; Biología Celular e Histología
Recently, the role of macrophages in tendon repair has received increased attention. These cells are versatile, playing multiple roles, such as defending the host, engulfing debris, producing growth factors, and releasing substances that can both promote and alleviate inflammation. Within the scope of tendon repair and tendinopathy resolution, macrophages are essential contributors. However, the current understanding of macrophage involvement in tendon healing remains limited. Hence, understanding macrophages' impact on tendon healing is of considerable importance for devising innovative treatment approaches. It is crucial to examine the precise role that macrophages play in tendon recovery, as it provides new understanding that can propel both research and the development of therapeutic methods aimed at enhancing tendon recovery moving forward