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Effect of mebendazole and ivermectin on the shedding of nematode eggs by three species of gazelles (Gazella dama mhorr, G. cuvieri, and G. dorcas)
( American Association of Zoo Veterinarians, 1995-07-07) Abaigar, Teresa; Ortiz, Juana; Cano, Mar; Martínez-Carrasco Pleite, Carlos; Albaladejo, Antonio; Alonso de Vega, Francisco-Domingo; Sanidad Animal; Facultades de la UMU::Facultad de Veterinaria
Mebendazole and ivermectin were studied for the control of gastrointestinal helminthiasis in three species of captive gazelles: Gazella dama mhorr, G. cuvieri, and G. dorcas. Ivermectin was given s.c. in a single 0.2-mg/kg live-weight dose and mebendazole was given in three dosages based on species: G. dorcas, 14 mg/kg; G. cuvieri, 6 mg/kg; and G. dama, 3 mg/kg orally twice daily for 3 consecutive days. Each drug was tested in 13 individuals of each species; 13 additional individuals served as untreated controls. Helminths detected by fecal examination and culture were species of Trichuris, Ostertagia, Cooperia, Trichostrongylus, Nematodirus, and Strongyloides. The prevalence among the total gazelle population was: Trichuris, 55%; Nematodirus, 26%; and other nematodes, 84%. After treatment with mebendazole, the nematode egg counts and the number of animals shedding eggs decreased moderately. After ivermectin treatments, there were marked decreases in the amount of eggs being shed and the number of animals shedding eggs of these nematodes.