(F. Hernández y Juan F. Madrid. Universidad de Murcia: Departamento de Biología Celular e Histología, 2015) Conte, Enrico; Fagone, Evelina; Fruciano, Mary; Gili, Elisa; Iemmolo, Maria; Vancheri, Carlo
Resveratrol, a natural polyphenolic molecule
with several biological activities, is a well recognized
anti-oxidant, anti-aging and cancer chemopreventive
agent. Moreover, resveratrol anti-inflammatory and
antifibrotic properties have been demonstrated both in
vitro and in different animal models of inflammatory
pathologies, including bowel and liver diseases. We
review the evidence of resveratrol protective role in
respiratory diseases such as acute lung injury, asthma,
chronic obstructive pulmonary disease and lung fibrosis.
We conclude that resveratrol and its derivatives may act
as a therapeutic agents in respiratory diseases and
pertinent clinical trials should be performed.