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GENERAL INFORMATION
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1. Title of dataset: 
Reduced hepcidin 1 of gilthead seabream (Sparus aurata): Immunomodulatory effects and implications in iron homeostasis


2. Author information:

[Fill in information for each author]
	Name: Claudia Marin Parra
        Institution: University of Murcia
        Email: claudia.marin@um.es
        
        Name: Jhon Alberto Serna Duque
        Institution: University of Murcia
        Email: jhonalberto.sernad@um.es
	ORCID: https://orcid.org/0000-0001-6962-3722

	Name: Laura García
        Institution: University of Murcia
        Email: laura.garcia12@um.es
	ORCID: 0009-0007-6678-8426

        Name: María Ortiz García
        Institution: University of Murcia
        Email: maria.ortizg@um.es
	ORCID: 0000-0002-8860-9181

        Name: Salvadora Martínez Lopez
        Institution: University of Murcia
        Email: salvadora.martinez@um.es
	ORCID: 0000-0002-4929-7533

        Name: Cristóbal Espinosa Ruiz
        Institution: IMIDA
        Email: cristobal.espinosa@carm.es
	ORCID: 0000-0002-3063-1634

	Name: Christopher R. Coxon
        Institution: university of Edinburgh
        Email: Chris.Coxon@ed.ac.uk
	ORCID: 0000-0002-3375-3901

	Name: María Ángeles Esteban Abad
        Institution: University of Murcia
        Email: aesteban@um.es
	ORCID:0000-0002-6264-1458

3. Date of data collection (single date or date range):
[2024-MM-DD]

4. Deposit date:
[2026-06-]

5. Language:
English



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METHODOLOGICAL INFORMATION 
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1.Description of the methodology used to generate the dataset.

In vitro assays: circular dichroism, antioxidant activity, bactericide, cytotoxicity and hemolysis.
In vivo assays: mucus humoral parameters, cellular parameters, gene expression and iron measurement in tissues.

2. Software or tools needed to interpret the data. 
[Include the version of the software. If specific software with restricted access is required, explain how to obtain it. Assess whether it is possible to change the dataset to an open format (recommended)]. 
Excel and Matlab.

3. Procedures followed for data quality assurance.

All procedures followed the protocols and statistical analysis are  indicated in the article-


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FILES
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1. File name: 
[List all the files included in the dataset, with the name and extension of each file (.csv, .pdf, etc.)].

DATASET_Hepcidin.xlsx

2. File format:

Excel



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KEYWORDS
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1. keywords:

Host defence peptides; Hepcidin 1; Iron; Immunomodulation; Disulfure bonds; gilthead seabream (Sparus aurata). 



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SPONSORSHIP INFORMATION AND GRANT IDs
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1. Grant Information:

CMP received a PhD grant (PRE2021-098414). MOG received a PhD grant (22303/FPI/23) awarded by the Fundación Séneca de la Región de Murcia (Spain) .CER received a grant from the Ramón y Cajal Fellowship Programme of the Spanish government (RYC2023-045252-I). This work was financed by the projects MCIN/ AEI /10.13039/501100011033 (grant number PID2020-113637RB-C21) and by the Comunidad Autónoma de la Región de Murcia-Fundación Séneca (Spain), and the Programa regional de fomento de la investigación científica y técnica de excelencia, en la Convocatoria de ayudas de la Fundación Séneca-agencia de ciencia y tecnología de la Región de Murcia a grupos de investigación de excelencia de la Región de Murcia para el desarrollo de actividades de investigación científica y técnica y de valorización y transferencia de conocimientos (23025/GERM/25). 

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RELATED PUBLICATIONS
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1. Related publication:

2. Related dataset:





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LICENSES AND PRIVACITY
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1. Licenses:

2. Privacity:





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MORE INFO
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 [Include any other information about the data set that is not reflected in this template and that is considered relevant.]